Suggestion for API Call for authentication

HI Team, Greetings of the day,

Currently we are using the API(Search & Tickets)  to search the user as well as ticket details and update that ticket too using HTTP call. 

To make API call, we are using Basic authentication like username and password. We are planning to implement the MFA for this account for security concern.

Is it possible to use this API with some sort of other authentication 

• without using the username or password with some sort of token.
• If we enable the MFA for the account, we are not able to directly use username and password.

https://--.zendesk.com/api/v2/users/search.json?query=@{variables('varUserEmailId')}

https://--.zendesk.com/api/v2/tickets/

Please suggest how I can make the authentication for this API.  Please let me know incase of any more information is required from my end.